As a high-performance bio-based material, nanocellulose shows broad application prospects in the fields of energy, environmental protection, biomedicine and other fields due to its unique nanostructure, excellent mechanical properties and degradability. Among the many preparation methods, the TEMPO oxidation method has become the mainstream technology for the preparation of carboxylated nanocellulose (TOCN) due to its high selectivity, mild reaction conditions and product stability. This article will systematically explain the technical points of preparing nanocellulose by TEMPO oxidation from the aspects of reaction principle, process flow, performance control and industrialization challenges. 1. Reaction principle of TEMPO oxidation method The core of TEMPO oxidation method is to use 2,2,6,6-tetramethylpiperidine nitroxide radical (TEMPO) as a catalyst, under the synergistic effect of sodium hypochlorite (NaClO) and sodium bromide (NaBr), to selectively oxidize the primary hydroxyl group (-CH₂OH) at the C6 position of the cellulose molecular chain, and convert it into

Today, as the biopharmaceutical industry accelerates its transformation to green, safe and efficient, nanocellulose is moving from the laboratory to the forefront of industrialization due to its natural renewable, excellent biocompatibility, complete degradability and other characteristics, becoming a key material to promote innovation in the medical and health field. As a company deeply involved in the field of nanomaterials, we are driven by technological innovation, focus on the biomedical track, and continue to explore the breakthrough applications of nanocellulose in drug delivery, tissue engineering, medical dressings and other fields to provide safer and more efficient solutions for clinical treatment. 1. Nanocellulose: the 'ideal carrier' for biomedicine. Traditional drug delivery systems often face challenges such as low absorption efficiency, poor targeting, and high toxic and side effects. Nanocellulose has become a high-quality carrier for drug delivery due to its unique physical and chemical properties. Its high specific surface area (up to 1000-5000 m²/g) and abundant hydroxyl groups on the surface can be used to chemically modify negative

With the rapid development of precision medicine and regenerative medicine and the increasing consumer demand for safe medical aesthetics and green medical materials, pain points such as biological rejection and residual toxicity of traditional medical materials have become prominent. Nanocellulose (Nanocellulose), which is biocompatible, degradable and high-performance, has become the core choice for the upgrading of biomedicine and medical aesthetics industries. It is used in fields such as wound repair and drug delivery. As a high-tech enterprise deeply involved in the research, development, production and application of nanocellulose, Nanjing Tianlu Nano Technology Co., Ltd. (hereinafter referred to as 'Nanjing Tianlu Nano'), relying on mature technology and large-scale production capacity, is promoting the industrialization of this green nanomaterial in the fields of biomedicine and medical aesthetics, assisting the high-quality upgrade of the industry, and practicing the development concept of 'green empowerment, technology-driven'. Nanocellulose is mainly divided into CNF cellulose nanofibrils, CNC cellulose nanocrystals, and BNC bacterial nanocellulose. The raw materials come from

Under the dual-carbon strategy, green renewable materials have become the core direction of industrial upgrading. Nanocellulose, as a new nanomaterial extracted from natural biomass, has become the key to solving pain points and upgrading the paper industry with its advantages such as environmental protection, high strength, and degradability. Nanjing Tianlu Nanotechnology focuses on the research and development and production of nanocellulose, empowering the high-quality development of the paper industry. Nanocellulose: Definition, Classification and Core Advantages Nanocellulose is a fibrous material that deconstructs natural cellulose to the nanometer scale (1-100 nanometers in diameter) through mechanical, chemical and other processes. The raw material is derived from natural biomass such as wood and straw. It is rich in reserves, green and degradable. It is mainly divided into three categories and is suitable for different application scenarios: • Cellulose Nanocrystal (CNC): High crystallinity, strong rigidity, suitable for high-strength coatings and precision composite materials; • Cellulose nanofiber (CNF): has excellent flexibility and good film-forming properties, and is the most widely used type in papermaking; •

Global plastic packaging pollution is becoming increasingly serious, and disposable refractory products cause a large amount of white pollution, which goes against the 'double carbon' strategy and the concept of sustainable development. Nanocellulose (Nanocellulose), as a new type of natural biomass nanomaterial, has become a core breakthrough in the field of degradable packaging due to its excellent barrier properties, film-forming properties and environmentally friendly properties. Nanjing Tianlu Nano Technology Co., Ltd. is deeply involved in the research and development, production and sales of nanocellulose, assisting the implementation of the degradable packaging industry and promoting the green upgrade of the industry. 1. Nanocellulose: the core preferred material of degradable packaging. The core requirement of degradable packaging is to balance environmental protection and practicality. Compared with traditional degradable materials such as starch-based and PLA, nanocellulose has significant advantages. Nanjing Tianlu relies on its characteristics to create customized products for multiple industries and realize material value conversion. 1. Extremely environmentally friendly, eliminating white pollution from the source. Nanocellulose is made from agricultural and forestry biomass such as wood, straw, and bamboo.

Against the background of the rise of new energy vehicles and energy storage industries, lithium batteries have become the core carrier of global energy transformation. The technological upgrade of lithium battery separators directly determines the development level of the industry. Due to shortcomings such as insufficient thermal stability and easy shrinkage at high temperatures, traditional polyolefin (PE/PP) separators are difficult to meet the needs of high-safety, high-energy-density lithium batteries. Nanocellulose (CNF/CNC), as a new green new energy material, has become the core choice for separator upgrades with its unique advantages. Nanjing Tianlu Nano Technology Co., Ltd. (hereinafter referred to as 'Nanjing Tianlu') is a domestic professional R&D and production enterprise in the field of nanocellulose lithium battery separators, assisting the green upgrade of the industry. Nanocellulose breaks the shackles of traditional separator technology and injects new momentum into the lithium battery industry by virtue of its core characteristics such as ultra-high thermal stability, ultra-strong mechanical strength, nano-scale porous structure and full life cycle green environmental protection. Nanjing Tianlu, located in Jiangning District, Nanjing, has been deeply involved in the field of nanocellulose for many years, relying on local

The demand for wound care is evolving from 'basic protection' to 'precise repair and efficient healing promotion'. Traditional dressings have difficulty in adapting to the needs of multiple wounds due to poor air permeability and easy adhesion. The emergence of nanocellulose has broken the technical bottleneck and become the core driving force for the upgrade of functional dressings. Nanjing Tianlu Nano Technology Co., Ltd. (hereinafter referred to as 'Tianlu Nano') is deeply involved in this field, using professional technology to promote the industrial application of nanocellulose in functional dressings, helping wound care enter a new stage of 'green and efficient'. Nanocellulose (especially bacterial nanocellulose BNC) has become an ideal substrate for functional dressings due to its high purity, three-dimensional network structure, excellent biocompatibility and degradability. Tianlu Nano focuses on the research and development and large-scale production of nanocellulose core technology and optimizes the preparation process. The nanocellulose substrate fibers it produces are uniform and stable in performance, and can achieve multi-functional modification, driving iterative breakthroughs in functional dressings from the root.

Nanocellulose is a nanoscale functional material prepared from natural cellulose. It has the characteristics of high specific surface area, excellent mechanical strength, good biocompatibility and degradability. In the field of medical and biomaterials, its unique physical and chemical properties make it a core material for promoting clinical treatment, tissue repair and biomedical innovation. Its application scenarios cover wound care, tissue engineering, drug delivery, medical consumables and medical aesthetic care. 1 Wound care field: Accelerated healing 'smart dressing' wound care is one of the earliest medical scenarios where nanocellulose has been industrialized. The core relies on the high purity and three-dimensional network structure of bacterial nanocellulose (BNC). 1.1 Chronic wound and burn care BNC dressing is breathable, moisture-permeable, and can absorb exudate. It can maintain a moist environment on the wound surface, promote cell proliferation and tissue regeneration, and can shorten the healing time by 30% compared with traditional gauze.

Nanocellulose: The road to innovation of green nanomaterials, Nanjing Tianlu helps the industry implement it. Today, with the 'double carbon' strategy in-depth advancement and the concept of environmental protection fully popularized, green materials have become the core direction of industrial upgrading. As a new biomass nanomaterial derived from nature, nanocellulose has broken the limitations of traditional materials with its core advantages of renewable, degradable, and high performance. It has achieved breakthroughs in papermaking, composite materials, biomedicine and other fields, and has become a key force in promoting the green transformation of the industry. As an R&D and industrialization enterprise focusing on the field of nanocellulose, Nanjing Tianlu Nanotechnology Co., Ltd. (hereinafter referred to as 'Nanjing Tianlu') is based in Nanjing. Relying on regional resources and technological advantages, it deeply cultivates this field and promotes nanocellulose from laboratory to large-scale application. It provides professional and efficient green material solutions for various industries and assists the high-quality development of the industry. 1. Nanocellulose: Nanocellulose, a 'green super material' derived from nature

In the context of the acceleration of the global 'double carbon' strategy and green manufacturing, bio-based materials are becoming the core direction to break resource constraints and reduce environmental pressure. Among them, bacterial cellulose (BC), with its unique nanoscale network structure, excellent physical properties and sustainable characteristics, stands out from many cellulose materials and has become a 'potential stock' that has attracted much attention in the field of new materials. As a natural polymer synthesized by microbial fermentation, bacterial cellulose is realizing large-scale applications in the fields of medical health, food industry, environmentally friendly packaging, flexible electronics and other fields with its core advantages of 'high purity, excellent strength, biocompatibility, and degradability', providing new solutions for the upgrading of traditional industries and the development of emerging industries. 1. Core understanding: The essence and unique properties of bacterial cellulose. Bacterial cellulose is produced by Acetobacter genus (such as Komagataeibact