In the long history of human exploration of materials science, from natural stones in the Stone Age to steel and plastics in the Industrial Revolution, every material innovation has promoted the progress of civilization. Nowadays, in an era when sustainable development has become a global consensus, a magical material derived from microorganisms, bacterial cellulose (BC), is quietly setting off a revolution in the field of materials with its unique performance and green and environmentally friendly characteristics. 1. Natural Creation: The Magical 'Loom' of Microorganisms Bacterial cellulose is not a new discovery of mankind. As early as the 19th century, French scientist Blanchard first observed the white gelatinous substance secreted by Acetobacter. This was the prototype of bacterial cellulose. But it was only in recent decades, with the development of microscopic analysis technology, that scientists truly unveiled its mystery. Unlike plant cellulose, bacterial cellulose is produced by specific microorganisms such as wood vinegar

As a high-performance bio-based material, nanocellulose shows broad application prospects in the fields of energy, environmental protection, biomedicine and other fields due to its unique nanostructure, excellent mechanical properties and degradability. Among the many preparation methods, the TEMPO oxidation method has become the mainstream technology for the preparation of carboxylated nanocellulose (TOCN) due to its high selectivity, mild reaction conditions and product stability. This article will systematically explain the technical points of preparing nanocellulose by TEMPO oxidation from the aspects of reaction principle, process flow, performance control and industrialization challenges. 1. Reaction principle of TEMPO oxidation method The core of TEMPO oxidation method is to use 2,2,6,6-tetramethylpiperidine nitroxide radical (TEMPO) as a catalyst, under the synergistic effect of sodium hypochlorite (NaClO) and sodium bromide (NaBr), to selectively oxidize the primary hydroxyl group (-CH₂OH) at the C6 position of the cellulose molecular chain, and convert it into

Today, as the biopharmaceutical industry accelerates its transformation to green, safe and efficient, nanocellulose is moving from the laboratory to the forefront of industrialization due to its natural renewable, excellent biocompatibility, complete degradability and other characteristics, becoming a key material to promote innovation in the medical and health field. As a company deeply involved in the field of nanomaterials, we are driven by technological innovation, focus on the biomedical track, and continue to explore the breakthrough applications of nanocellulose in drug delivery, tissue engineering, medical dressings and other fields to provide safer and more efficient solutions for clinical treatment. 1. Nanocellulose: the 'ideal carrier' for biomedicine. Traditional drug delivery systems often face challenges such as low absorption efficiency, poor targeting, and high toxic and side effects. Nanocellulose has become a high-quality carrier for drug delivery due to its unique physical and chemical properties. Its high specific surface area (up to 1000-5000 m²/g) and abundant hydroxyl groups on the surface can be used to chemically modify negative