As a novel biological material, bacterial cellulose has its unique nanofiber network structure that imparts excellent mechanical properties, biocompatibility and degradability. It has shown huge application potential in biomedical, food, cosmetics and other fields. The traditional static cultivation method has problems such as low production efficiency and high cost, which is difficult to meet the needs of industrial production. In recent years, the introduction of dynamic fermentation technology has brought new opportunities for the large-scale preparation of bacterial cellulose. This article will discuss the key influencing factors and optimization strategies in the preparation of bacterial cellulose from the perspective of dynamic fermentation. 1. Dynamic fermentation: Break through the limitations of static culture. The traditional static culture method uses shallow dish culture, and bacteria form cellulose membranes on the surface of the liquid culture medium. This method is simple to operate, but has many limitations: low production efficiency, uneven product thickness, poor quality transfer efficiency, etc. Dynamic fermentation technology significantly improves the mass transfer conditions through the introduction of stirring, ventilation and other operations, and improves the
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