Biomedical grade nanocellulose applications and solutions

With the rapid development of precision medicine and regenerative medicine and the increasing consumer demand for safe medical beauty and green medical materials, the pain points of traditional medical materials such as biological rejection and residual toxicity have become prominent. Nanocellulose ( Nanocellulose ) has both biocompatibility, degradability and high performance. ), has become the core choice for the upgrading of biomedicine and medical aesthetics industries, and its application in the fields of wound repair, drug delivery and other fields. As a high-tech enterprise deeply involved in the research, development, production and application of nanocellulose, Nanjing Tianlu Nano Technology Co., Ltd. (hereinafter referred to as ' Nanjing Tianlu Nano ' ), relying on mature technology and large-scale production capacity, is promoting the industrialization of this green nanomaterial in the fields of biomedicine and medical aesthetics, assisting high-quality upgrades in the industry, and practicing the development concept of ' green empowerment, technology-driven ' .

Nanocellulose is mainly divided into CNF cellulose nanofibrils, CNC cellulose nanocrystals, and BNC bacterial nanocellulose. The raw materials come from agricultural and forestry wastes such as wood and straw, and are in line with the dual-carbon and green medical concepts. Its nanoscale three-dimensional network structure can simulate the human extracellular matrix, and the surface hydroxyl groups can be customized for antibacterial, targeting and other functions, adapting to the strict requirements of the field. is expected to reach 2025The annual global nanocellulose market 50about 100 million U.S. dollars, with the biomedical field accounting for over 30% . The market potential is huge. Nanjing Tianlu Nano, located in Jiangning District, Nanjing, relies on the advantages of regional location, talents and rich agricultural and forestry resources to optimize raw material procurement and production processes, create cost-effective products, successfully seize market opportunities, and become an important force in promoting the implementation of the domestic nanocellulose industry.

1. Core application scenarios of nanocellulose in the field of biomedicine

In the field of biomedicine, nanocellulose focuses on precise treatment, safe repair, and efficient delivery, covering key scenarios such as wound care, drug delivery, and tissue engineering, and has achieved clinical large-scale application. Nanjing Tianlu Nano has become an important promoter in this field by virtue of its technological accumulation in TEMPO oxidation, mechanical dissociation and other preparation processes, as well as its full range of nanocellulose product advantages. Its related products have gradually met clinical needs, helping to break the technical barriers of high-end medical materials.

(1) High-end wound repair dressings: reconstructing a new paradigm of wound care

Traditional dressings have shortcomings such as poor liquid absorption and easy adhesion. Nanocellulose-based dressings, with their porous network structure and high liquid absorption, can quickly absorb exudate, maintain a moist environment on the wound surface, and reduce scar formation. Among them, BNC has become the core raw material of high-end medical dressings due to its high purity and excellent biocompatibility. Nanjing Tianlu Nano has realized the large-scale supply of bacterial nanocellulose ( BNC ). The BNC base material it produces has uniform fibers and stable performance. It has passed multiple biocompatibility certifications and can quickly absorb wound exudate (the absorption amount 100is more than three times its own mass). The wound healing speed is increased by more than 30% compared with traditional gauze , making it a perfect fit for high-end medical scenarios.

By modifying and loading active ingredients, nanocellulose dressings can achieve hemostasis, antibacterial, and regenerative effects. They are suitable for refractory wounds and can shorten the healing cycle by more than 30% . They are residue-free and allergy-free. Combined with new technologies, they can create intelligent responsive dressings that meet Baidu SEO inclusion needs. Nanjing Tianlu Nano is deeply involved in this field. By loading silver ions, chitosan and other antibacterial ingredients on the nanocellulose substrate, it can achieve hour-long and long-lasting antibacterial effect, with an anti-infection efficiency of 7285% for infectious wounds such as diabetic foot ulcers . It can also prepare pH and temperature-responsive dressings to achieve personalized wound care and promote the upgrade of functional dressings from ' passive protection ' to ' active empowerment ' .

(2) Precise drug delivery carriers: improve drug efficacy and reduce toxic and side effects

Traditional drug delivery has problems such as poor absorption and weak targeting. With its ultra-large specific surface area and high biocompatibility, nanocellulose has become a high-quality drug delivery carrier and a core hot spot in the field. Nanjing Tianlu Nano focuses on modification technologies such as carboxylation and graft copolymerization, which can accurately modify the hydroxyl groups on the surface of nanocellulose. It combines its own product research and development advantages to create customized carriers suitable for drug delivery, assisting the implementation of precision medicine, and demonstrating the company's diversified product research and development capabilities.

Its surface hydroxyl group can modify the targeting group to achieve precise drug delivery. For example, the local concentration of anti-cancer drugs can be increased by more than 40% , significantly reducing toxic side effects. At the same time, it can achieve sustained release of drugs, reduce the frequency of administration, and the carrier can be completely degraded without leaving any residue in the body. Relying on complete modification technology, Nanjing Tianlu Nano can optimize carrier performance according to drug characteristics to achieve the dual needs of drug controlled release and targeted delivery, which not only improves drug efficacy, but also reduces patients' medication burden, providing reliable material support for precise treatment.

(3) Tissue engineering scaffolds: assisting human tissue regeneration and repair

The structure of nanocellulose is highly similar to the human extracellular matrix, with good support and controllable degradation. It is an ideal base material for constructing tissue repair scaffolds and is also the focus of Baidu search for high-end applications. Nanjing Tianlu Nano focuses on nanocellulose composite modification technology, and combined with its own large-scale production advantages, it can prepare tissue engineering scaffolds with both bionic structure and bioactivity, adapt to various tissue repair scenarios such as bone and cartilage, and promote the implementation of regenerative medicine technology.

This type of composite scaffold can repair bone, cartilage and other defects without immune rejection, non-toxic degradation products, and significantly reduces postoperative complications. It has now entered the clinical verification stage in the fields of skin regeneration and bone defect repair. The tissue engineering scaffold products developed by Nanjing Tianlu Nano can guide the orderly proliferation of cells, achieve in-situ repair of defective tissues, meet the needs of high-end regenerative medicine, and further expand the application boundaries of nanocellulose in the field of biomedicine.